Polyclonal sera are made from a mix of monoclonal antibodies that target the same antigen but with a different affinity and specificity.
Depending on the application it is necessary to be able to isolate, charaterize and produce specific monoclonal antibodies.
It is possible to isolate antibody producing cells by performing fusion of these cells with a myeloma cell line to develop hybridomas.
Isolated and cultivated hybridomas produce a specific monoclonal antibody that can be the characterized, produced and use in different applications including diagnostic, purification, and therapeutic.
Delphi Genetics can provide to you different services associated to monoclonal antibody development: